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Various forms of pharmacotherapy have evolved to assist in the treatment of opiate addiction. According to The Development of Medications for the Treatment of Opiate and Cocaine Addictions, and in recognition of the need to improve availability of medications that can be used in the treatment of drug addiction, the Anti-Drug Abuse Act of 1988 in conjunction with NIDA authorized funds to help improve the availability of medications to be used in the treatment of opiate addiction, including those now used in Codeine addiction treatment.

Methadone and Suboxone are two medications that are used to treat codeine addiction.
Today, the following medications are often used in Codeine addiction treatment:
Buprenorphine
According to NIDA, Buprenorphine was approved by the FDA in 2002 and is regularly used in medically assisted opiate detox today. This medication has been found to help patients taper off their use of Codeine and successfully and safely withdraw with reduced risk of relapse.
Clonidine
A blood pressure medication that is commonly used in codeine addiction treatment on a short-term basis, Clonidine is sometimes used to shorten withdrawal times. According to Harvard Health, this medication can help to relieve physical symptoms of Codeine addiction but should only be used short-term; this medication is not safe for prolonged use.
Methadone
Codeine addiction treatment often involves the use of maintenance medications such as Methadone which reduce cravings and withdrawal symptoms. According to the CDC, methadone:
- Blocks the sedating effects of opiates such as Codeine
- Stops cravings for Codeine
- Relieves the symptoms of Codeine withdrawal
- Restores balance into the user’s life
- Stops drug seeking behavior
Suboxone
A combination of buprenorphine and naloxone, Suboxone reduces opiate use, improves recovery times and can help to restore balance into the patient’s life. This medication is often used as a stepping stone in Codeine addiction treatment to help the user get back on track. According to the University of Nevada, Suboxone provides patients with little to no euphoria but can greatly reduce symptoms of withdrawal.
Naloxone
According to the National Library of Medicine, Naloxone is used to reverse the effects of drugs such as Codeine. This medication can be used to treat opiate overdose but its ability to reduce the euphoric effects of Codeine and other opiates has made it widely used in addiction treatment. Patients are given Naloxone to reduce their desire to use because the drug prevents any excitement or euphoria from occurring when the drug is used thus rendering the drug use no longer “fun” or “enjoyable.”
Benefits of Counseling in Codeine Rehab -
Codeine is an opioid pain reliever used to treat mild to moderate pain and coughs. It is usually found in combination with other analgesics such as aspirin or acetaminophen, guaifenesin, an expectorant, or promethazine, another central nervous system depressant. How Does Codeine Work? Codeine is a central nervous system depressant that slows down activities in ...
Benefits of Suboxone as Codeine Addiction Treatment -
Suboxone, a drug that contains naloxone and buprenorphine, is often used as a part of the treatment regimen for codeine addiction. Along with therapy and counseling, it can be great treatment for codeine addicts, especially because of the many benefits it has as a pharmacological treatment. Low Abuse Potential Suboxone actually has a very low abuse ...
Benefits of Suboxone as Codeine Addiction Treatment -
As stated by the FDA, “Suboxone is a prescription medicine used to treat adults who are addicted to (dependent on) opioid drugs… as part of a complete treatment program that also includes counseling and behavioral therapy.” Suboxone can be used to treat addiction to illicit opioids like heroin and also to treat prescription opioid addiction. ...
Codeine Uses -
There are a number of medical uses for codeine but its primary use is for the treatment of mild to moderate pain. Sometimes, codeine is also prescribed as a cough suppressant and the medication can be found in smaller doses in many over-the-counter cough suppressants. Codeine is usually used in combination with other medications such ...