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Codeine is an opioid narcotic analgesic that is recommended in the treatment of mild to moderate pain and coughs. In short term treatments, codeine may cause a relatively minor physical dependence. However, in long term use or abuse, it can cause a harsher physical dependence as well as psychological dependence which may increase the risk of addiction.
Codeine Medications
The potency of codeine compared to morphine is about 10% and in pure form, codeine is a Schedule II narcotic, however most codeine products contain less than 90 mg of codeine and are classified as Schedule III drugs except in cough syrups containing less than 200 milligrams of codeine or per 100 milliliters which are Schedule V drugs, according to the DEA.
Codeine products used to treat pain may be combined with other ingredients such as acetaminophen or aspirin to enhance the analgesic effects and reduce harmful risks including abuse. Codeine cough syrups are combined with expectorants and antihistamines and are a favorite pastime for some abusers.
Codeine Effects
Codeine acts as a central nervous system depressant to reduce pain and cough stimuli, but, it also depresses other functions and can decrease breathing or heart rate which can be significantly dangerous. According to the Food and Drug Administration, “Some people metabolize codeine much faster and more completely than others.” Codeine side effects may include relaxation, drowsiness, dizziness, sedation, constipation, nausea, impaired cognition, and declined motor functions. In higher doses, codeine can produce euphoria.
Physical Symptoms of Codeine Dependence
The more codeine a person takes the greater their tolerance will become as their bodies adapt to its use and tolerance is marked by decreased effectiveness. Codeine dependence increases with tolerance and is recognized when withdrawals occur after discontinuing use.
Physical withdrawal symptoms are usually minor compared to other opioids and produce symptoms of nausea, headache, chills, stomach pains, sweating, or fatigue.
Psychological Symptoms of Codeine Dependence
When you are dependent on codeine you’ll feel sick after a day or so without it.
Psychological dependence is much more complicated and can occur when the brain becomes adapted to the repeat codeine use. All opioids increase dopamine in the brain which helps to regulate behaviors and reinforce those that bear repeating such as eating, or having fun.
Evidence shows that drugs which increase dopamine levels above normal can cause the person to experience cravings for the drug and psychological withdrawals when they are discontinued.
Psychological withdrawals from codeine abuse may include agitation, restlessness, anxiety, and sleep disturbances.
Some behavioral changes from psychological dependence may include:
- Fear of running out of codeine
- Obsessing over next dose
- Denying or hiding the amounts used or frequency of doses
- Using fraudulent means to obtain more codeine
- Social withdrawal or isolation
- Need to use codeine to feel normal
- Loss of interest in activities not involving codeine use
Signs of Codeine Tolerance -
Codeine is a narcotic analgesic that can be obtained directly from opium or though a methylation of morphine. It’s most common uses are for treatment of mild to moderate pain and to relieve persistent and painful coughs. Like its counterpart, morphine, codeine has the potential to produce tolerance after only a few uses. Codeine for Pain ... 
Codeine and Pregnancy -
As with many other drugs that are passed on from the mother to unborn fetus, Codeine use should generally be avoided during pregnancy to ensure the safety of both mother and child. At this time, the actual safety of codeine use by pregnant women has not yet been determined and therefore should be avoided whenever ... 
Codeine Side Effects -
Generally, the side effects associated with codeine use are mild and do not require immediate medical attention. In some cases, if the side effects do not go away in time or with discontinued use of the drug, or if you suffer from certain side effects while taking codeine, medical attention will be required. Codeine is an opioid ... 
Side Effects of Codeine Cough Syrup Addiction -
It has become a popular trend in recent years to abuse codeine cough syrup by mixing it with soda or alcohol. This combination, according to the University of Texas, is sometimes called lean, “for the side effect causing users to lose their coordination.” This drug has many side effect of its use and, unbeknownst to ... 
Side Effects of Codeine that Need Medical Attention -
Codeine exists as one of many opiate-based pain relief drugs. Unlike many prescription pain medications, codeine comes directly from the opium poppy seed plant. As one of the less potent opiate drugs, codeine became the first opiate-based medication to be sold as an over-the-counter product. In spite of its widespread availability, codeine carries the same ...